What is High Intensity Focused Ultrasound (HIFU)?

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High intensity focused ultrasound represents a non-invasive, minimally invasive therapeutic approach. Utilizing intense, highly focused sound waves, it interacts with targeted body tissues, aiming to alter or destroy them. Primarily, high intensity focused ultrasound addresses diseases such as tumors, uterine fibroids, and tremors.

High intensity focused ultrasound encompasses Magnetic Resonance-guided high intensity focused ultrasound (MRgHIFU) and ultrasound-guided high intensity focused ultrasound (USgHIFU). A study from the "Korean Journal of Radiology" in 2018 comparing MRgHIFU and USgHIFU revealed equivalent data on feasibility, safety, and effectiveness in the complete ablation of low-intensity T2 fibroids for the treatment and outcomes of uterine fibroids.

principle of  tumor treatment used by focused ultrasound

Figure 1. The principle of  Tumor Treatment used by Focused Ultrasound

High intensity focused ultrasound can be likened to using a magnifying glass to focus sunlight on a target area. It concentrates ultrasound beams on the exact tissue needing treatment, causing a rise in tissue temperature. This specific heat is enough to destroy (ablate) the targeted tissue area. Moreover, the ultrasound beams can penetrate layers of tissue, such as skin, without causing harm; they accurately target diseased tissue, sparing healthy tissue from damage. Distinguished from chemotherapy, radiation therapy, and open surgery, High intensity focused ultrasound is a non-invasive, radiation-free treatment option, generally safer than other treatments. However, high intensity focused ultrasound is not suitable for all types of tumors, especially if cancer cells have spread or if tumors are difficult to visualize with imaging.

Focused transducer

Figure 2.HIFU transducers manufactured by Siansonic Technology

Currently, high intensity focused ultrasound is widely used to treat various diseases, including certain solid malignant and benign tumors, uterine fibroids, and drug-resistant primary tremors.

Siansonic Technology, with 38 years of experience in ultrasound device manufacturing, supplies a range of focused piezoelectric ceramic plates and HIFU transducers for applications in high intensity focused ultrasound.


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