Functional Coating Layers in Biosensors, Microfluidic and Other Diagnostic Testing Kits

As growing industry of point-of-care, in-vitro diagnostic devices, need for precision coatings of active and non-active functional layers onto these devices is rapidly increasing. 

Ultrasonic spray nozzles can spray onto targeted areas uniformly in ultra-low flow rate. Ultrasonic coating technology are highly controllable and repeatable, able to deposit precise thin films of solutions or suspensions such as biopolymers, proteins, EDTA, Heparin, amino acids, enzymes, blood plasma and preservatives.

Figure 1：Hydrophilic Coating on Biosensors Deposited by Ultrasonic Spray Coating

Siansonic ultrasonic coating systems can be used for:

• Reagent coatings onto microfluidic devices

• Hydrophilic and hydrophobic coatings onto microfluidic devices 

• Point-of-care diagnostic and testing kits

• Cell culture vessels

• Blood glucose monitors

• Blood collection and analysis devices

• Molecular and protein diagnostic kits

• Immunoassay kits

Advantage of ultrasonic coating technology:

• Reduced consumption of raw materials.

• Non-clogging ultrasonic nozzles reduce servicing and downtime.

• Highly controllable, reliable, repeatable

• Capable of coating ultra-thin, specific patterns

• Soft spray with ultra-low kinetic energy, no damage on most delicate cellular structures

Figure 2：Industrialized Ultrasonic Spray Coating Solution for Biosensor

Benchtop and industrial ultrasonic coating systems are full solutions for production of IVD device coatings. From R&D to volume production, these coating systems which can be equipped with Siansonic all series ultrasonic nozzles match various size and geometry substrates. Siansonic always aims to develop a full coating solution to the specific application of IVD device manufacturers by working with them.